Depends on your terrain, stand or drive/stalking.
I have 2 barrels one open sights for close in deer drives/stalking fast action and a long range scoped barrel. I personally prefer a scope because I use the long range slugs and I can zoom in and check the rack or confirm a doe as I ready for shot. I like to sit in tree stand or on high point over looking travel routes ,hunt in deer safety zones and escape routes while everyone else pushes them around.